Yesterday I was attending as an anesthesiologist for a very old lady having a very long surgery. ENT surgery for cancer with a brachial freel flap reconstruction. I have to say that I do not know nothing about this medical litterature but I write this as quick memo for later. There also some tidbits about scarring.
- what about giving aspirin one week before the surgery ? does the risk of more transfusion outweights the benefits ?
- what about giving NO donors before the surgery or at least NO rich food like beetroot concentrate ?
- what about aiming for an hematocrit between 27 and 30 % for good hemorheology ?
- what about maintaining a good mean arterial pressure and keeping a very shallow window of 60-70 mmHg ?
- is there a place for intravenous isorbide dinitrate during surgery ?
- is there a place for rinsing the flap with heparinized solution and or nitrates ?
- should we use more albumin or fresh frozen plasma to preserve glycocalyx of the microcirculation in the flap ?
- in the post-operative ward, might photobiomodulation with red or more seriously infrared lights help tissue metabolism ?
- should we encourage even more patients to move after the surgery to rise cardiac output ?
- is there a place for zinc and ascorbic acid supplementation or proline to enhance collagen production ?